Which statement best describes the requirement before starting animal research?

Which statement best describes the requirement before starting animal research?

• A. A protocol must be approved by IACUC
• B. A protocol must be submitted to IACUC only after the study begins
• C. A protocol does not require IACUC review if the study is short
• D. A protocol can be approved by the investigator alone

Answer: (A)

Before starting any animal research, the protocol must be approved by the IACUC. This formal review protects animal welfare and ensures the study is scientifically justified, that the number of animals is minimized, procedures are humane, and all aspects of care, housing, training, and veterinary oversight are planned and compliant with applicable laws and policies. Work cannot proceed until IACUC approval is granted, and approval cannot be given by the investigator alone or retroactively if procedures have already begun. Even short studies require review, and ongoing or updated protocols undergo continuing review. This process reflects efforts to minimize pain and distress while promoting responsible use of animals in research.

Before starting any animal research, the protocol must be approved by the IACUC. This formal review protects animal welfare and ensures the study is scientifically justified, that the number of animals is minimized, procedures are humane, and all aspects of care, housing, training, and veterinary oversight are planned and compliant with applicable laws and policies. Work cannot proceed until IACUC approval is granted, and approval cannot be given by the investigator alone or retroactively if procedures have already begun. Even short studies require review, and ongoing or updated protocols undergo continuing review. This process reflects efforts to minimize pain and distress while promoting responsible use of animals in research.