Which policy governs use of vertebrate animals in federally funded research?

Which policy governs use of vertebrate animals in federally funded research?

• A. Animal Welfare Act (AWA)
• B. Public Health Service (PHS) Policy
• C. GLP Regulations
• D. USDA Regulations

Answer: (B)

For vertebrate animals used in federally funded research, the governing framework is the Public Health Service Policy on Humane Care and Use of Laboratory Animals. This policy applies to all vertebrate animals used in research, teaching, or testing when the project is funded by PHS agencies like the NIH. It requires institutions to have an IACUC to review and approve animal use, ensure humane housing and care, provide appropriate veterinary oversight and personnel training, and conduct annual IACUC reviews with reporting. The policy is implemented through the Office of Laboratory Animal Welfare, which ensures the institution has a compliant Assurance. While the Animal Welfare Act (enforced by USDA) covers many welfare aspects, and GLP regulations address study conduct and data integrity, the specific framework governing federally funded vertebrate research is the PHS Policy.

For vertebrate animals used in federally funded research, the governing framework is the Public Health Service Policy on Humane Care and Use of Laboratory Animals. This policy applies to all vertebrate animals used in research, teaching, or testing when the project is funded by PHS agencies like the NIH. It requires institutions to have an IACUC to review and approve animal use, ensure humane housing and care, provide appropriate veterinary oversight and personnel training, and conduct annual IACUC reviews with reporting. The policy is implemented through the Office of Laboratory Animal Welfare, which ensures the institution has a compliant Assurance. While the Animal Welfare Act (enforced by USDA) covers many welfare aspects, and GLP regulations address study conduct and data integrity, the specific framework governing federally funded vertebrate research is the PHS Policy.