What is the term used to describe a situation where new genes are inserted by a targeted mutation?

What is the term used to describe a situation where new genes are inserted by a targeted mutation?

• A. Rederived
• B. Hemizygous
• C. Knockin
• D. Wild type

Answer: (C)

In genetics, when new gene sequences are added at a precise genomic location, the process is called a knockin. This means the introduced DNA is integrated at a targeted spot in the genome, often to express a reporter, tag a protein, or study a gene’s function while keeping the original gene present. It’s different from a knockout, which disables or removes a gene rather than adding something new. Wild type refers to the normal, unmodified genome. Hemizygous describes having only one copy of a gene in a diploid organism, not about inserting new material. Rederived isn’t the term used for targeted insertion.

In genetics, when new gene sequences are added at a precise genomic location, the process is called a knockin. This means the introduced DNA is integrated at a targeted spot in the genome, often to express a reporter, tag a protein, or study a gene’s function while keeping the original gene present. It’s different from a knockout, which disables or removes a gene rather than adding something new. Wild type refers to the normal, unmodified genome. Hemizygous describes having only one copy of a gene in a diploid organism, not about inserting new material. Rederived isn’t the term used for targeted insertion.